In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.
نویسندگان
چکیده
منابع مشابه
In Vivo Suppression of NF - k B and Preservation of I k B a by Interleukin - 10 and Interleukin - 13
IL-10 and IL-13 have powerful antiinflammatory activities in vitro and in vivo. In the IgG immune complex model of lung injury in rats, exogenously administered IL-10 or IL-13 have recently been shown to suppress neutrophil recruitment and ensuing lung injury by greatly depressing pulmonary production of TNF a . Transcriptional control of the TNF a gene is regulated by the nuclear factor kappa ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1997
ISSN: 0021-9738
DOI: 10.1172/jci119786